Search on: PREGNANCY-ASSOCIATED ALPHA 2-MACROGLOBULINS 
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Descriptor English:   Pregnancy-Associated alpha 2-Macroglobulins 
Descriptor Spanish:   Alfa 2-Macroglobulinas Asociadas al Embarazo 
Descriptor Portuguese:   Alfa 2-Macroglobulinas Associadas à Gravidez 
Synonyms English:   Pregnancy-Associated Alpha 2-Globulins
Pregnancy-Associated Alpha 2-Glycoproteins  
Tree Number:   D12.776.124.790.720.100.500
D12.776.780.675
Definition English:   Large (>160 kDa) glycoproteins with electrophoretic mobility of ALPHA-GLOBULINS, found in high concentration in the plasma of pregnant women but also in a number of species including mouse, rat, and others (ALPHA-MACROGLOBULINS). In humans, they are always present in the circulation and are nonspecific inhibitors of PROTEINASES, similar to COMPLEMENT PROTEINS (C3; C4; C5). 
History Note English:   2004 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   38251 
Unique Identifier:   D045384 

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